I saw my dr today to go over 3 month labs and almost everything looked good. I was diagnosed with an a1c of 10ish (I can’t remember what the point number is) in the summer of 2024. This entire year I changed my eating habits, exercised a little bit more, and started feeling a tad better. We didn’t have insurance so I couldn’t pay Monjauro out of pocket so I am taking Metformin and glyburide. My a1c after my recent blood draw is at 5.9. We have insurance now and my dr wants to put me on Monjauro. My question is this: I’ve managed to get my a1c under control so far so do I really need the Monjauro? She seems to think the benefits are tremendous but I’m not sure. I know y’all aren’t doctors but wanted to get some thoughts from people who have diabetes and are taking Monjauro or from those who would like to be able to take it. Thanks.
The benefits ARE tremendous. It makes controlling your diet so much easier and not everyone loses a crazy amount of weight while taking it.
I lost just over a stone in 2 months my Hb1ac went from 113 to 49 my sugars range is 3.9 - 10 and it’s never been out of range in the last 7 weeks
I started Monjauro with an a1c of 6.6 and a month later I was down to 5.2. Two months after that and I'm down to 4.8 and my doctor said it'll be stabilizing soon. My dad is also diabetic and just started Mounjaro after years on regular meds. He was averaging an a1c of 11 and now he's down to the 6 range (in about a month or two on the lowest dose). Since you're already doing the work to help yourself, Mounjaro is definitely a tool that'll help boost the positive work you're doing. It is something to heavily consider, though, because from what I hear, it's a lifetime drug. You can go into maintenance and take doses once a month after everything is stable, but if you stop taking it, your weight will come back and I'm not sure if your a1c will skyrocket but it's a possibility.
Does that mean you can eventually stop taking the meds?
I think the majority of folks will be taking it for the rest of their lives. It’s why I didn’t want to try it but I also didn’t have tons of weight to lose to be a normal weight (only 40lbs). My cousin dropped 125lbs in a year on it.
Same here! I don’t need to and even shouldn’t be losing weight. I was pre-diabetic before pregnancy but my Dr didn’t flag it. Got gestational diabetes during pregnancy and then full blown diabetes post pregnancy. Right now my new Dr told me to try with diet and exercise. It is controlled with diet and post meal walks but I have to be extremely careful with my diet, like no more than 30-45g of carbs/day.
Same. I walk after every meal and do about 50 carbs a day which I could easily drop down under 30 but I really love my ninja Creami protein ice cream after dinner which has a half cup of Fairlife milk in it. I’m just not ready to give that up yet but my last A1C was 5.2 and I think my next one might even be under 5. :)
I’ve been taking Mounjaro for two years. My a1c is great (8.3 down to 5.1). I have lost a ton of weight. I can basically eat like a “normal” person, in that I don’t really worry about carbs anymore. And you only have to take it once/week. I haven’t really had a lot of bad side effects. It’s my favorite thing.
Honestly, if you have consistent health insurance now and will for a while, its worth seeing if it’s beneficial for you. I haven’t had to do the Rx dance with my situation (for now), but I made massive improvements with nutrition changes, increased exercise, and Ozempic alone. Zero side effects too (but my gut is kind of made of steel, so it was unlikely to cause me nausea). Down from 9.2 A1C at diagnosis to 5.0 in just three months, lost 20lbs nice and steady (not too fast). I imagine that mounjaro would be similar, just with faster/greater weight loss. That said, if what you’re on now is tolerable, effective, and affordable - mounjaro might just be a better option in your toolbox for later. No need to change if what you’re doing is working, right? Unless there are side effects to Metformin and Glyburide that your Dr is trying to reduce?
Ask your Doctor to explain why she wants you to take it. Be specific, not just “the benefits are tremendous”. Your A1C is good, you’ve been doing well with diet, lifestyle and excitement improvements, what exactly is broken that Mounjaro is required to fix? He’s love to pump patients full of meds but you should just be sure you really need it now because it doesn’t sound like you to.
The benefits of Glp drugs is not the effectiveness. Metformin and diet changes can do that too. But it is in reducing the constant cravings.
It does sereral things simultaneously,
1) slows your gut so you eat less 2) smooths your glucose spikes, because it is processed slower 3) lowers you glucose because you eat less 4) loose weight because you eat less, which starts a beneficial feed back loop.
It doesn’t just work by slowing your digestion. It also stimulates insulin production, inhibits the release of glucose by your liver and improves your insulin resistance. It does quite a lot of things that come together to lower your glucose levels.
I've been on either Ozempic or Mounjaro for the last 3 years. However, I started on it immediately vs. trying other treatment options so I don't have anything else to really compare it to. I was an 11 at diagnosis. I've been at 5.3 the last couple of years. I did also change my diet pretty drastically and now have consistent exercise. I dropped from around 210 to a little under 170 at 5'9".
I guess one question would be, how well do you tolerate those two drugs? And does your doctor or you want to drop any additional weight? Or to further drop your A1C? You will most likely do both if you switched/added it.
For me it's also resolved a digestive issue I had as well. Not sure why. For that reason alone I will stay on it as long as I can.
I went from 10.2 to 5.1 in three months with a combo of mounjaro, diet changes (lower carbs), and exercise. I also lost 50 pounds, and have continued to drop about a pound a week since.
Check if your insurance covers it as a diabetic and if so apply the cost savings program too. Mine is about $57/month and worth every penny. But it could be more/less for you of course. You can also look into other brands of GLP1s covered by your insurance.
Glp-1s are beneficial in many ways besides glucose control. Lowers risk of cancer, heart disease, also helps with addiction issues including binge eating, improves inflammation and joint pain, I've even seen some say it helps their ADHD (no clinical data on this yet but lots of anecdotal data). I don't know if you deal with any of these issues but I definitely recommend trying it for a few months if it's affordable. Side effects taper off of time typically too.
Metformin loses its effectiveness over time so lots of providers are recommending GLP1s as first line of treatment now. Great job on all the hard work and awesome results!
I have a couple of thoughts to add to the great feedback already offered.
First, when I was diagnosed with T2, I also had some test results that showed my liver was being taxed. I started on Metformin, which helped drive down my A1C, but seemed to exacerbate the toll on my liver.
I dropped the Metformin, started on an escalating dose of Monjauro, and continued to drive down my A1C (from more than 12 to less than 6), while improving my liver health. So one benefit- for some of us - is avoiding the toll meds like Metformin can take on the liver.
Second, Eli Lilly has a program for setting off a substantial part of the cost of you’re taking Monjauro for T2. I just received a text about it this evening:
“From Lilly: As of 12/22/2025, you are enrolled in a Mounjaro® (tirzepatide) Savings Card Program.
The Mounjaro affordability program has been extended through 12/31/2026.
No additional actions are required, and you can continue using your current savings card. If you continue to meet the eligibility requirements, you can continue to save.
Be on the lookout for the updated full terms and conditions before 12/31/2025 here: https://e.lilly/mjosavings
See Indications and Safety Summary including Warnings: https://e.lilly/4iB89XW
Reply STOP to opt out. Msg & Data Rates May Apply”
I was on it and could eat pretty much anything I wanted except for cereal and oatmeal. And juice. I lost 191 lbs. My friend is on it and loves it. I had to quit because I just Never ate. But I was on it for 3 years I have gained 3 lbs back. I’d try it again from the start.
My doc and I discussing going o n monjouro my ai1 is 6.2 with januvia. He was suggesting for stok and liver protections as well as A1c. I have a friend with liver disease she's on ozempic and her number are vastly improved
5.5 A1C, did a year on Trulicity and switched to Mounjaro 2 months ago. I do eat mostly low carb but I can also eat a pasta dish or desert when I want. It’s very worth it in my opinion.
Personally, I would take it.
What I like about it is that it is a peptide that gives your body the signals it's missing to deal with glucose itself. It's not blocking some function or doing something different than what's natural. It's simply providing what you are missing if you didn't have T2.
Without knowing your weight or age, if you feel confident you can continue, tell your doctor. I know my doctor would go with me, but listen to your doctor and then discuss and decide. You can always start Mounjaro later.
I had problems on the MJ (close to bowel obstruction) and it happened twice. First time I needed heavy antibiotics- official diagnosis was diverticulitis, threatened obstruction. I seemed obstructed for hours, was in agony as bad or worse than when I delivered my first child. Followed by watery D that lasted days (which was a relief as the pain gradually subsided too but a nagging abdominal pain lasted weeks). Had to go off the MJ for several months. Doc then wanted me to try again, then 3 days in on my second dose that second attempt with MJ, it seemed to be starting again. I’ve had slowed gastric emptying in the past but never the sense of blockage with violent vomiting so suddenly and nothing coming the other way, with severe pain, other side. My point is there are downsides to the MJ for some people. Not denying it is a miracle drug for many, but if you can bring your a1c down without it that’s great too. My husband is still on his and has lost weight but he has very unpleasant side effects at times (not like mine though - I was close to being admitted to hospital that first round on MJ - my second episode, round 2, I just stopped eating solids, was only liquids for days until the MJ cleared a bit from my system, but I was scared! Btw I did lose weight (30 lbs from round one in just a few weeks), and it has all stayed off , I’m no longer obese ‘just’ overweight now- it’s been many months I’ve been totally off the MJ. I will try to keep losing without the MJ. Whatever you decide, good luck.
Btw I was on it for weight loss, husband had elevated A1c, both our A1c numbers are normal now and mine is v low now! Husband is thinking of going off his soon just to have his digestion return more to normal - he has to take fibre constantly and suffers frequent C with some unpredictable D. It’s the lack of predictability that bothers him.
Hi! So my A1C was around 6.1. Slightly overweight, but not obese, around 180 for a person who's 5'7". I took Mounjaro for a month, and the weight came off pretty quickly. It's a potent drug, and I was experiencing some lows, so I stopped using it, though I may consider going back on it or Ozempic if the weight comes back or my A1C jumps up. It's been very steady recently, and I've made significant changes to my diet, cutting out most carbs. Everyone's reaction is different, and it's a personal choice whether you do it.