Hey everyone,

I’m looking for some feedback on my current stack. I have idiopathic hypersomnia and treatment-resistant depression and have been on various stimulants for years, so my tolerance is pretty high. I’m trying to build an energy + motivation stack that’s safe, sustainable, and actually noticeable.

Here’s what I’m currently taking:

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🧠 Prescription Meds (all taken at night): • Cymbalta • Vraylar • Gabapentin • Norethindrone (progesterone) • Levocetirizine (antihistamine)

Taking them at night helps avoid daytime sedation.

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⚡ Morning (current routine):

Upon waking: • Nuvigil (Armodafinil)

20 minutes later (with a snack): • Vitamin D • B-complex • Multivitamin • CoQ10 • ALCAR (500–1000 mg) • L-Tyrosine (500–1000 mg) • Sabroxy (starting with 50–75 mg, working up to 100–150 mg) • Optional but considering adding: KSM-66 Ashwagandha (300 mg)

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🌤️ Midday (as needed): • Sabroxy microdose (25–50 mg) • Hydration + protein • Light movement

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🌙 Nighttime Supplements (2–3 hrs before bed): • Agmatine (500–1000 mg) • Ashwagandha (400 mg, standard form) • Magnesium (optional)

📌 Context / Goals: • I have high stimulant tolerance from long-term use • I deal with low motivation, low energy, and hypersomnia • I’m sensitive to anxiety but not really sensitive to stims anymore • I’m trying to rebuild dopamine sensitivity and get functional daytime energy • Looking for advice on adjustments, additions, or safety considerations

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❓ Questions for the community: 1. Does this stack look balanced with my prescription meds? 2. Any thoughts on adding KSM-66 to the morning while keeping regular ashwagandha night only? 3. Would Rhodiola or Ginseng be worth exploring, or too stimulating on top of Nuvigil + Sabroxy? 4. Any recommendations for improving wakefulness without spiking tolerance further? 5. Anyone else with hypersomnia or TRD find a stack that finally moved the needle?

Thanks for any feedback — I’m trying to optimize without overdoing it, and I’d love input from people who’ve been in the trenches with dopamine/tolerance issues.

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  • At night I'd replace Ashwagandha with L-Glycine & L-Tryptophan respectively.

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