PHOTO EXAMPLES IN COMMENTS.

Seems to happen more if in dehydrated. I’ll add photos in the comments, but yeah. Pretty much that, my blood is clotting as soon as it registers into the syringe. This isn’t old blood eventually clotting and clogging it, this is straight from registering pulling out alarmingly large formed blood clots. My boyfriend says it’s way way opposite of normal, and that he’s never seen it before. I don’t have a clotting disorder. Im not the best at staying hydrated, but I do use clean and new needles and supplies each time, test my product, and inject properly..

(Yes I am in the process of getting clean, I have an awesome support system and access to so many resources, MAT, meetings, and support groups. I admire anyone who is on a sobriety journey and appreciate anyone who will encourage me to be on mine, but things don’t happen in a day. I’m easing into things.)

I’ve never seen anyone have this problem or had a tin look the way mine look when I’m done!! Why is this happening?

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  • Those clots are not forming in your body, and they are almost certainly early fibrin strands rather than what people typically think of as pathologic blood clots. They form immediately after the blood leaves your vein. The moment blood is exposed to air and to plastic or metal surfaces, the coagulation cascade begins, and this is further amplified by the negative pressure created when pulling back on a syringe. Under these conditions, clotting can happen so quickly that it forms thick, string/worm like material, which can look alarming but is not something to be overly concerned about in itself.

    This does not mean you have a clotting disorder, and it does not increase or predispose you to systemic clot risk such as DVT, PE, or stroke. What it does increase is the risk of local vascular injury, including endothelial damage, superficial thrombophlebitis, vein sclerosis, and injection-site complications. These are localized processes and do not imply clots circulating through your bloodstream.

    It is likely more noticeable for you because this effect is strongly influenced by dehydration and methamphetamine-induced vasoconstriction, both of which increase blood viscosity and reduce blood flow velocity, promoting faster clot formation once blood exits the vein. Additionally, strong or repeated aspiration (while drawing back to register) under low-flow conditions allows fibrin strands to form at the needle tip before the syringe fills.

    This does not mean you have clots floating around in your circulation. If you did, you would have clear symptoms such as unilateral limb swelling, pain, or redness, chest pain with breathing, shortness of breath, coughing up blood, or sudden neurologic changes. There is no indication for a hypercoagulable workup unless symptoms suggest a true clot.

    As general advice, stay well hydrated, avoid forceful or repeated draw-back when registering, rotate injection sites, warm the area beforehand to improve blood flow, and reduce overall use. All of these will help minimize this effect. And above all, please consider treatment.

    Hope this helps.

    Thank you! I don’t use meth like I do fentanyl, and I notice it a lot more when I use meth, because then I’m more dehydrated as well. My veins are pretty shot from my using, and I’m stopping before I do anymore permanent damage. What I have done so far (besides probably collapse a few veins) is all reversible, so I’m still lucky for that. I’m going to a methadone clinic, I’m just now stabilizing on my dose where I don’t feel like I’m dying and sick from withdrawal, which makes stopping a lot easier. I’m weaning myself off the fent but staying comfortable, because being dope sick just restarts the cycle for me. I’ve done it a few times clean using clean using, and I want long term recovery this time. I have an awesome support system here, and I know who to reach out to and the resources available, I have a plan for myself, the day I will stop completely and what I will do. If that day comes and I continue, I plan to go inpatient to really kick it. Thank you for all your knowledge!

    OP, I really commend the work you're putting in towards your sobriety. Im also so, so happy to see you are using harm reduction techniques in your use while youre transitioning to MAT. You seem very educated on the transition,I just wanted to add (also for any possible other readers this applies to) to be honest with your clinic about your current use so they can help prevent any precipitated withdrawal, which can be absolutely brutal. Best of luck to you on your journey to sobriety!

    I wish I could say “__ was my rock bottom input it down forever…” but that’s just not my story. And that’s okay. I admire those so much who are able to out it down whatever way they were able to. In my personal case, that energy that I put toward using, and the time and effort I put in.. it’s gotta be transferred. It doesn’t just go away, I have to find new outlets to exhaust that energy. It’s such a big part of my life and lifestyle, I mean my day revolves around it. So I’m slowly replacing my activities and hobbies with healthy ones, and replacing my actions as well. Lastly comes replacing my thoughts but that just takes time. The more positive outlets I have to take the place of my addictive behaviors the better my result is… like I said for me it’s all about creating a present and future I want to be present for, not nod out during :) I appreciate the kindness and support!

    But yes, being honest with healthcare professionals has helped a ton. I have not experienced any judgement on my use, actually they said it’s expected while I stabilize and just recommended I keep narcan and test strips, noting that benzos can be extremely dangerous mixed with methadone. Small steps in the right direction eventually add up, there’s no one way ticket to get there

    NAD I have a small clotting disorder I've been prescribed low dose aspirin for.

    Would that help in this case or cause more harm from the excess bleeding aspirin causes?

    So I’m def NAD I’m the poster lol but someone told me once to actually take aspirin as it’s a blood thinner before I use to lessen the thick blood and clots!!

    NAD, but aspirin is a platelet aggregate meaning it just makes your blood slippery. It’s actually being studied to determine if it actually helps in cases of acute MI (heart attack) as there’s been some discrepancies.

    I truly commend your commitment to kicking the addiction. I lost my sister in 2013 to an accidental OD. Managed to get clean, get a full ride to college, was a double major, and her scholarship was through a PhD or JD. Your support system cares about you and wants you to succeed, as do we! I’m sure you know, it’s going to be hard & there will be days you want to give up. Don’t. Keep persisting to see the light at the end of the tunnel. I promise you, life will become infinitely better once you stop chasing the high and if I’m wrong, you can kick my ass. Always ask for help if you’re struggling, there is absolutely NO shame in that. If you can get to NA meetings, do it. Surround yourself with people who inspire you, who have kicked the addiction & forget those who try to drag you down. They just want your money & don’t care what happens to you, but your support won’t want your money—they want you to experience a life free from this.

    Also, there’s been an executive order signed designating fentanyl as a WMD (weapon of mass destruction). Not sure when it goes into effect, but something to keep in mind. I’m rooting for you, OP, and I’m sending you prayers.

    YOU CAN DO THIS!

    Yeah I just wanted a doc to chime in before suggesting it, since it's a complex situation way outside my area.

    It's also something you can't control after doing it, as the blood thinning effect lasts longer than 24h which is plenty of time for you to die from something I didn't think of.

  • 6 years sober here. There’s a way off this ride if you want it.

    That’s awesome!! I’m getting there.. slowly replacing and stabilizing on methadone. Replacing old habits with new actions I don’t need to run away from and avoid. Learning to love myself enough that I don’t need to poke holes in myself and create a life I don’t need to nod out from.

    Wishing you all the best in your journey.

    Almost 2yr clean and 2,5 years into methadone treatment.

    I took everything super slow. Like we usually have daily pickups for 3months (as long as you're not constantly relapsing) but I think I did it for 6-9 months (to avoid starting abusing the meds, i knew myself well enough to see what would happen if i started having it at home without being mentally ready) and overall spent sooo much energy on being honest with the clinic about my mistakes and emotional state

    Sounds cliché, but they can't help unless you tell them what's going on and instead of them being pissed/suspicious of me we've built a very supportive and honest "relationship"

    This is the first and only time I've actually made real progress

    NAD and I know I'm just jumping in without any real answers, but just wanted to add what's been working for me, just in case it could help

    Thanks, it’s reassuring! Really. Because no two recoveries are the same, there’s not a one size fits all method really that is going to work for everyone bc everyone’s experience is so different. Different pain tolerances, different pains experienced too.. I am also taking it slow. I’m not in a rush because I know how I am. I’m better implementing little things each day and practicing them until they become habit than just flipping everything upside down and “changing” overnight. I am being super mindful though that I don’t want to get stuck and be tapering for 6 months lol and just use it as an excuse to still use! My counselor has been super supportive as has my doctor of my switch from how much I was doing daily to how much I dropped down to, as I continue my journey off the fent. The methadone is a true life saver.

    You are awesome! :)

    You can do it. Get to an NA meeting. Share honestly, the rest will follow. Godspeed. 7 years sober here.

  • Yes your blood can behave very differently under these conditions, and what you’re seeing is most likely rapid fibrin clot formation, not a “worm” or foreign material. Several things you mentioned strongly predispose to this.

    When blood hits air or a foreign surface (like a needle or syringe), the coagulation cascade starts immediately. In your case, it’s happening abnormally fast, forming thick fibrin strands that look ropey, gelatinous, or worm-like.

    Fascinating. Does this predispose the patient to experiencing complications from clots for a short period? For example, a stroke, heart attack, PE, DVT.

    Absolutely, it’s extremely important they discontinue IV drug use ASAP and hydrate properly. Easier said than done, but from a medical standpoint this is a huge warning sign.

    I figured the fact that I have clots forming like this wasn’t a sign of good health, but it’s another sign to stop while these things are reversible.

    Exactly, this should be more of an “ohh shit” moment tho rather than another sign to move in the right direction. I can’t speak to the difficulty of overcoming an addition like this, but I can speak to your situation medically. I want to be clear, this could potentially kill you at any moment. If you develop a fever, chest pain, swollen leg, worst headache of your life, dramatic vision changes, head straight to the hospital.

    My hands and feet also fall asleep like all the time, especially when in certain positions. Sitting on the toilet would cause my legs and feet to fall asleep, often after I had a batch of fent that would make me nod out on the toilet for a week, until I woke up with numb or tingling legs….

    I know a guy who lost a leg. He tells a different story every time (shark bite, fight, dinosaur bite.. none are true lol) and the story is he fell out on the toilet, and lost circulation for good. And he lost his leg. Could this happen? Could that be true?

    Yes, absolutely he could have landed in such a position that blood flow to the leg was diminished. Usually when that happens it causes enough discomfort that a person moves themselves into a different position. If he wasn’t able to do that because of injury or impaired sensation, then that can lead to permanent tissue death and limb amputation. I’ve heard it referred to as “rock star arm” injury.

    That’s so scary. I’ve had many times I haven’t been able to get up right away because of the numbness in my legs and tingling. Waking up folded over my legs on the ground, unable to feel them. The other day my plug was stuck like that for a good 45 minutes. He was like that when I left. It scared me pretty good and reminded me of the seriousness

    So the “fibrin,” is that the tanish whitish swirls I get in my blood? Or can fibrin be dark dark blood colored as well?

    Both. Fibrin is not a single color.

    This isn’t a permanent issue and it doesn’t mean you are clotting like this internally, but your chances of clotting internally is certainly much higher.

    To stop this you need to hydrate better and stop IV drug use, which I’m assuming you already know. It is reversible. Not to scare you, but this is a sign that you need to handle this sooner rather than later.

    My boyfriend was so alarmed when he saw the clots and the size… I figured it was from dehydration and really going hard with the needles. I’m grateful so much of the issues I have will go away once I put the drugs down. I’m getting there. Not everyone takes the same path to recovery, mines a bit slower as I wean off the fentanyl and increase methadone till I’m only on the methadone, but I’m getting there:) thanks so much for your knowledge!

    I’m 13yrs off of H and my husband off methadone 11yrs. I went cold turkey off the H which was BAD. 10/10 do not recommend. And he ended up going to a 6mos in patient rehab center and that was after going to rehab to get off H the first time for 6mos relapsing and then methadone. If we can do it so can you two. replacement therapy (methadone and subs) doesn’t work for everyone (it doesn’t work for most people). I have seen with my own two eye so many people die trying to work those types of programs. so please if you don’t feel like it’s working don’t let it just be a legal high. Sober living only works if you’re alive to do it. The symptoms you are having are not good and are not normal. That’s not slow down signs. That’s hard stop signs. Take care of yourself and each other. One day at time. And when that’s too hard, one hour. And when that’s too hard, one minute. But they all add up.🫶🏻

    I know I need something in the transition period for sure, I tried cold turkey and there was just no way I would willingly go through that if I didn’t have to… I’ve done this many times before, so I kinda know myself. I’m willing to try anything though, if it will work. If I get to my stop completely date and I’m still using fent, I’m checking into treatment again. If I’m staying clean, then I’ll continue my treatment as outpatient. I also am considering moving into an Oxford house when my lease is up. I’ve achieved longer term sobriety in the past when I had it in my living space, surrounded by the sobriety and support of others. ❤️ I also know all the amazing resources and kind souls on the internet who are always willing to talk and help. I appreciate the advice so much. It helps a lot not being alone.

    I am 10 years off of heroin (SO grateful that fentanyl wasn’t really a thing on the streets at the time I was using) and I just wanted to jump in and tell you that treatment will be nicer than you think. I was so afraid to get clean, and one of the factors was that I was extremely resistant to the idea of being in rehab for a long time. I did the methadone clinic, IOP, therapy, 12 steps, the whole works before I actually went to inpatient treatment. In my opinion, all of those great outpatient resources are really only helpful if you are able to get off the drugs first. For me, actually stopping meant going inpatient. And they had me go to a medical detox first, and I transitioned to sober living after. The biggest surprise to me was that I had been so afraid and resistant to going inpatient, but when I got there I actually found it so nice and absolutely necessary to get away from my life for a while. 30 days seems like forever, but it’s really not and it goes quickly. If you’re able to go inpatient for longer, it’s even better to stay 90 days or even 6 months. It isn’t just better than you expect, but it’s actually very enjoyable. I hesitate to say it’s fun, but you will be surprised how much you actually like it.

    NAD. Seconding that inpatient treatment is the way. I have enjoyed my time at inpatient and have created friendships and a support system. I joke that it's like summer camp for drunks.

    Such a kind response.

    Im 8.5 years clean off H , just before fent got really big. If I can do it you can. I wish you the best.

    I had 8 months, and I celebrated them… I’m currently on methadone. Dosing myself down with fent, and increasing my methadone as I stop the fent, I tried a few months ago but damn… even on 85 mg the methadone didn’t TOUCH the withdrawal. That used to be a pretty high dose I guess… I’m more comfortable now, I’m more stable at 145 mg methadone, and I am down to 3x a day fent, tomorrow is another 3x a day, then I start 2x… slowly. If that doesn’t work back to rehab. But I have faith in myself. As long as I commit to a community and building a life I don’t need to escape from, and use the resources and people who make it possible, I think I can do it:)

    Yea I think support and community is key at the beginning. It sounds like you've got this. I am so glad that you havent given up. I believe in you!!!

    Chiming in saying I know 2 people who are clean off H. Seems like it's not easy but it is doable and worth it. The people I know are doing much better now in life overall. There was nothing special about their circumstances other than the fact that they chose to leave it behind and followed through. OP can definitely get there imo.

    Yep. Everyone i know, including myself, who got clean, were just regular addicts. Nothing exceptional or unique about any of us. We just happened to try and maybe get enough steam behind us to begin to see the benefits and have the depression and destruction begin to lift. Absolutely not easy but if OP wants it they CAN do it. And dont give up if there are bumps in the road. Most people do mess up as they seek to get better.

    Id follow that up though to add that I dont know of a single person who stopped using/broke and addiction who hadn't decided for themselves that they didn't want to do it anymore. I still know a lot of addicts, and many claim they dont want to continue with the addiction but they also use the addiction as an excuse not to quit it, if that makes sense? The only way imo to truly come off a particular substance is to definitively decide once and for all that youre done with it, otherwise we just waste our own lives lying to irselves about our habbits and addictions and how we're "better than we were... " xyz. Thats not to say that relapses dont happen, just that if and when they do, if your mindset is still focused on recovery, its much much easier to jump back on the wagon.

    Congrats! Very happy for you and proud!! I lost my sibling to H overdose over a decade ago. Wouldn’t wish that pain on anyone’s family.

    Im very sorry for your loss. Terrible.

    When I was in ICU and I've my tesio line flushed - they'd have to do it because they'd have to prevent clots and aneurisms.

    Could be something like this, either way you need to stop this shit. Easier said than done. 16 months sober (drugs)! You can do it too!

    ❤️ congrats! I’ve had time before, this last relapse turned into a longer than expected (always is,) rodeo. But I’m slowly coming off. Decreasing the fent as I stabilize on methadone till I’m 100% off it. I have an awesome recovery community and meetings by me, and there’s so many amazing people in recovery online who are more than happy to help out, listen, and be a friend. ❤️ so I know I can do it as long as I reach out to support before I reach out to the plug

    I've been around a few people while they kicked cold turkey, and it was brutal. I'll never forget my one 24-year-old friend sort of delirious and crying for her mommy. Back in the day, people in the 12-step programs were shitty to those who did it with methadone, but things have changed now. Don'tt let anyone give you a hard time about it, using less is progress, and using medical intervention still gets you off dope, out of dangerous situations, money in your pocket, and a better life.

    I've seen this before, BTW, in IV meth and cocaine users. One ended up having endocarditis, and the other had bacteremia (bacteria in the blood stream). Both eventually became very ill and 1 died. Just saying...take extra good care of your body for awhile. Whether it'dehydaration, a reaction with something in the contents of the syringe, or a brewing more serious problem, you won't lose out by eating well and hydrating.

    I had a pretty gnarly run with sepsis a couple years back. I went to visit my plug on my way home from the hospital… different people have different stopping points. Mine is just that it’s simply not working anymore. I started using to escape everyday life, escape trauma, escape myself, I started using to avoid and not face anything. It was effective until it wasn’t. Now I’m creating a life I don’t need to escape from, because my main addiction is avoiding. I avoid everything uncomfortable, and I was uncomfortable in my own skin. I’m working more on becoming comfortable and creating habits and actions that I don’t need to numb out to face. Starting a life that I don’t want to run from and healing from all the past avoiding and running is the ultimate reward. Just don’t want to struggle anymore, waste money… I want to love myself enough not to put holes in my body but it doesn’t happen overnight!

    I’m sorry if this is a triggering question, and don’t answer if you don’t feel comfortable. Writing in spoiler tags just in case. Those going cold turkey from opioids, how long do the withdrawal symptoms last? Is it a week, a month? Months? Do you still feel shitty a year later?

    When I went cold turkey off H it was awful for a week. I was delusional. Couldn't stop moving my legs. Hallucinating. Puking. Shitting. Sweating. Shivering. Everything hurt. Yawning constantly. Then it starts to ease up a bit. Idk if post acute withdrawl symptoms are different if you go cold turkey or if you use a medication. But I had them for about a year afterwards when I got clean this last time around with the help of subs

    One person I know still gets withdrawal symptoms for a day after taking even one opiate pill, even with 15 years clean. They've had a lot of health issues requiring pain control over the years and manage the meds very carefully.

    Not a year. Maybe emotionally raw after a year, I can only speak for myself. Coming off heroin, actual heroin, was 3 days. By the 3rd day I was able to pick up again. Coming off subs, I did a taper, and withdrawal was 3 days and very mild because I tapered down slowly all the way to like 0.2 mg.

    Fentanyl? I haven’t been able to cold turkey. Even with the 85 mg of methadone it took a week earlier this summer for the sweating nausea restless legs irritability and insomnia to subside and become very mild. This Fentanyl is no joke. It’s strong and my tolerance is just so high… I hear methadone is also a hard one to come off. Most people taper down 1-2mg every week, which is what I’ll do whenever I get off. A long slow gradual taper is always best

    Just another sober person who is also saying, if I can, so can you OP ❤️

  • I'm NAD, but I work in harm reduction and overdose prevention. I've been sober for a few years now. I spent most of my 20's and the first years of my 30's in and out of chaotically using IV fent/H.

    My blood acted the same way in my last 2 years of IV drug use. Other people thought I was exaggerating or that I was delusional. Once I stabilized enough to address my underlying health issues, I found out that I had undiagnosed sleep apnea, which elevated my hemoglobin and hemocrit levels. I still have lots of scar tissue, but I'm healthy enough to donate blood (which decreases those levels) regularly now.

    With the drug supply as contaminated as it is in the United States, it's important that you're using safe injection practices as much as possible. A lot of the agents used to cut fentanyl currently are awful for vein health. Some fentanyl analogues are more damaging than others. Injecting IV 🧊⛸️ is also tough on veins (as I know you already know). Veins can harden from scar tissue, collapse, and develop small holes from repeated injections to the same spots. I developed abscesses from bacteria in my shots that leaked from my veins to soft tissue. Once a person who injects drugs (PWID) gets an abscess, they're at higher risk of developing them again in the future.

    None of the following info is being given to "condone" someone's substance use. Getting off drugs is one of the hardest things I've done, and I had many "unsuccessful" attempts. Any positive change is a step in the right direction, and it deserves to be celebrated. Abstinence as the only pathway to recovery does more harm than good.

    While you're tapering down, it's important that you are staying hydrated as much as possible and rotating injection sites. If you decide to use more than usual after your tolerance has gone down, be sure to have someone check on you before and after you use. Your risk of overdosing goes up significantly after tapering down for 48 hours. Have naloxone (aka Narcan) somewhere in plain sight like on your lap. If you use with another person, be sure you both have your own naloxone. Taking hot showers or doing some cardio like jumping jacks before you try to inject will make your veins easier to access. Do not use nicotine when you're about to inject. Nicotine is a vasoconstrictor, making your veins harder to access.

    Do you have access to a harm reduction service provider? If you use a tourniquet, be sure to undo it before you inject. Use a new syringe as frequently as possible. In a perfect world, I would tell you to use a new point for every shot. Idk how much you're using, but you may need a bigger cooker so your shots aren't so concentrated. As for clogging the needle, use a smaller gauge (so a thicker needle). I know that 28-31 gauge is most common for PWID, but I had to go down to a 27 gauge to keep from regularly clogging the needle.

    If you have other questions or you'd like some resources on safer injection practices/harm reduction/how to get free naloxone, feel free to DM me.

    Adding to that make sure that whoever lives with there knows how to administer narcan and put someone in a recovery position and to note what time they gave it while calling for help. Having it on hand is awesome but knowing how to use it is doubly. when I did my mental health first aid training renewal half the class had their person laid out or hunched over and left them that way the whole time. 😳 🫣

    I do have harm reduction services and resources near by! They’re awesome. I appreciate the advice and the honesty. It’s usually when I use more meth, and I am more dehydrated my blood does this a lot more.. I didn’t have great bulging veins to start with but they are total shit now. They have to ultrasound my arms at the hospital, when I was sick they had to go in my neck (though over the summer I think I collapsed that one too..)

    I’m tired of the pain and suffering, desperation, spending money, sadness, apathy, and the routine. I started using because it was effective, it changed my mood and me, it changed whatever I was doing. It made things tolerable and made me comfortable. But as my tolerance increased so did my tolerance for the dangerous things I allowed to happen to me/I participated in. They’ve become less effective and not enjoyable anymore, what is enjoyable is the idea of a life I don’t have to escape from with a substance.

    I appreciate the tips on needle safety too! We have a great exchange with a ton of resources. Like I said my veins are shit, but I’d like to not do so much more damage these next 14 days as I taper more. That addiction is one in and of itself, just the needle fixation. But I am pretty determined and stubborn when i set my mind to it, so as long as i keep the goal in mind and use my resources and community, i can do this ❤️

    We carry both nasal and intramuscular narcan in every room and on our person where I live. It’s saved my boyfriend a few times and me a few times as well. ❤️

  • NAD.

    14 years clean from IV heroin. Man the last year of my using this was a daily occurrence. I had about 3/4 min before this happened after every draw up. My veins were angry and my body was done. I got a terrible infection in my bones at the end of my using that about killed me. That was the end for me. Happy to hear you have all the safeguards but you know you gotta get clean for good. There is no happy ending for active use.

    It’s gotten to the point where it’s not even giving me pleasure, the whole reason I used in the first place. It’s no longer effective in the ways it used to be. It just brings pain and misery and ugly reminders of an ugly reality and future if I continue. My body, mind, and spirit are just done. I’m just tired. I’ve been getting signs from my body and the world around me that it’s time to give it up. There is no happy ending with a needle in my arm

    You’ve got this. Putting it down for good was the easiest part! It was staying clean that was the hardest. But after I got to where you are right now, my spirit being done (what was left of it) is what pushed me to finally say fuck it. Because hello, it couldn’t get any worse??? I’m not saying that in a patronizing way, I feel like you hear what I mean lol. Sending many positive vibes to you, OP. The help is there, just gotta put the shit down and give yourself a fair shot at living. You deserve it 🫶🏼